Hyaluronic Acid (Sodium Hyaluronate)

Hyaluronic Acid

1. Cosmetic and Skincare Manufacturing

Hyaluronic Acid is commonly used as a key ingredient in moisturizers, serums, and anti-aging products.
Steps:

• Choose the Right Grade: Select the appropriate molecular weight (low, medium, or high) based on the desired product benefits.
• Hydrate Before Use: Dissolve HA powder in deionized water or hydrosols to create a gel or liquid base. Use a mixer to ensure proper dispersion.
• Incorporate into Formulation: Add the hydrated HA during the water phase of the product formulation to ensure stability.
• Dosage: Typical usage is 0.1% to 2% of the total product formulation, depending on the product type.

2. Pharmaceutical Manufacturing

HA is used in medical products like eye drops, wound dressings, and injectable fillers.
Steps:

• Sterilization: Use pharmaceutical-grade HA that meets regulatory standards for safety and purity.
• Hydration and Preparation: Prepare HA solutions in sterile environments, ensuring proper hydration and homogeneity.
• Incorporate into Product: Use HA as a viscosity modifier, moisture-retention agent, or active ingredient in products like:

3. Haircare and Personal Care Products

HA is a popular ingredient in shampoos, conditioners, and hair masks for hydration and smoothness.
Steps:

• Mix with Water Phase: Add HA during the water phase of the formulation process for haircare products.
• Combine with Other Actives: Pair with humectants like glycerin or panthenol for enhanced hydration.
• Recommended Dosage: Use at 0.1% to 0.5% for haircare formulations.

4. Food and Nutraceutical Industry

HA is used as a dietary supplement for joint health and skin hydration.
Steps:

• Select Food-Grade HA: Ensure the HA is suitable for consumption and meets food safety standards.
• Mix into Beverages or Capsules: Incorporate into powders, capsules, or functional beverages.
• Dosage: Follow regulatory guidelines for HA dosage in consumable products (typically 50-200 mg per serving).

5. Industrial and Specialized Applications

In specialized manufacturing, HA is used in biomaterials, tissue engineering, and 3D printing for medical applications.
Steps:

• Hydration and Sterilization: Prepare sterile HA solutions tailored to the application.
• Combine with Polymers: Use HA as a biocompatible additive in hydrogels, scaffolds, or other biomedical materials.

General Manufacturing Tips

• Storage: Store HA powder in a cool, dry place to maintain its stability and effectiveness.
• Mixing Equipment: Use high-shear mixers for uniform hydration and dispersion.
• Testing: Conduct stability and compatibility tests to ensure HA integrates seamlessly into the final product.
• Compliance: Adhere to regulatory standards (e.g., FDA, EU guidelines) for HA use in cosmetics, pharmaceuticals, or food.

• Form - Powder

For external use only. Avoid contact with eyes. In case of irritation, discontinue use and consult a physician. Keep out of reach of children. Store in a cool, dry place.